In 2021, the market for Cell Culture worldwide was worth $23 billion US dollars. AMR Group projects that the market will reach US$ 62 billion by 2031, growing at a CAGR of 13 percent between 2022 and 2031.
Industry Overview
Cell Culture is the technique of isolating cells from a plant or an animal and growing them in a controlled in vitro environment. However, this artificial environment has the vital nutrients necessary for cell proliferation and growth, which involves the temperature, gases, pH and humidity. Tissues can be mechanically or enzymatically removed of their cells prior to cultivation. The cells that are need to be grown could also be isolated from an established cell line or cell strain.
The cell culture market has various consumables and equipment’s required at different stages of the cell culture technique to understand the basic biochemistry and biology of cells. It works as a model system and can be used for different applications such as cancer research, stem cell research, bio production, diagnostics, and drug screening. The market is driven by factors such as the growth in biopharmaceutical market, growing demand for monoclonal antibodies, increasing prevalence of chronic diseases, increase in research funding, and rising adoption of single-use technologies. In addition, disposal of plastic waste generated from single-use technologies, cell line misidentification, and cross-contamination hamper the growth of this market to a notable extent. Recent developments in gene expression technologies have provided the production of novel vaccines and biopharmaceuticals, thereby increasing the research & development applications of cell culture techniques.
Market Dynamics
The Cell Culture market tends to grow due to the increasing investment in the R&D by the major market players in development of new cell culture product is anticipated to propel the market growth. In 2021, Pall Corporation, a global supplier of separations, filtration, and purification of products announced that Pall Corporation and Cytiva, had jointly invested US$ 400 million in cell culture media. Also, increasing approvals of strategies like acquisition by major players operating in market is expected to fuel growth of the cell culture market. Cell-based research studies helped to understand the cells' responses to any chemical and identify novel components that can be used for people's well-being.
In past years, Cell biology involved extensively in R&D on new therapies of gene therapies and stem cell. The reagents, equipment, and other products related with research and analysis must be of the highest quality and proper condition to provide the most accurate results. The growing need to maintain high-quality standards and comply with guidelines set up by regulatory bodies, the cost of cell biology research has raised considerably. Thus, high cost for the process is a restraining factor in the global cell culture market.
COVID Impact
The COVID-19 pandemic has mildly impacted the Cell Culture Markets major pharmaceutical and biotech companies. As they collaborated to find vaccines and treatment methods during the pandemic as well. The idea behind the collaboration was to make partnerships and evaluate solutions as early as possible during the pandemic period which could not be completely possible with any one organization alone. Joint ventures also took place within universities and companies to speed up the research and production process. Outsourcing of pharmaceutical and biotechnological research to contract research organizations (CROs) also increased during the pandemic. In April 2020, AstraZeneca and Oxford Biomedica plc signed an agreement for the global development and distribution of the University’s potential recombinant adenovirus vaccine, however the development & worldwide manufacturing and distribution of the vaccine was the responsibility of AstraZeneca.
Regional Trend
Geographically, the global Cell Culture market is segmented into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. Globally, North America dominates the Cell Culture market due to high research and development investments, the presence of a well-established scientific infrastructure, significant demand for animal component-free media, and other factors. In 2021, North America had the largest revenue share of 40% across the world. Asia Pacific is anticipated to register a higher due to the increasing healthcare expenditure, growing awareness regarding cell & gene therapies, and a huge potential for clinical research applications available in this region. In addition, the surge in adoption of scientific technologies and therapeutics, like cancer immunotherapies and regenerative medicines are likely to strengthen the industry's growth in the coming future.
Competitive Landscape
Key players operating in the global Cell Culture market are Agilent Technologies, Inc., Avantor, Inc., Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., BioSpherix, Ltd., Bio-Techne Corporation, Corning Incorporated, Cytiva, Eppendorf SE, FUJIFILM Holdings Corporation, Getinge AB, Greiner Bio-One GmbH, HiMedia Laboratories, Lonza Group Ltd., Merck KGaA, Miltenyi Biotec B.V. & Co. KG, PromoCell GmbH, Sartorius AG, Thermo Fisher Scientific, Inc., and VWR International, LLC among others. Recently, in January 2022, BioIVT introduced its GMP Grade Human AB Serum specialized for gene therapy manufacturing. Top companies in the market are Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, Inc., and Becton, Dickinson, & Company can significantly drive the market.
Key USP’s-
In January 2022, Cytiva (Danaher Corporation) collaborated with Nucleus Biologics for the development of custom culture media for cell and gene therapies. Expansion of the existing service offerings is being undertaken by emerging players to increase their market presence.
Market Segmentation
Based upon the Product used in cell culture market is segmented into two major segments Consumables and Equipment in the cell culture process. Further it is categorized according to its process and utilization. Based on application, the cell culture market is segmented into Bioproduction, Drug Screening & Development, Cancer Research and Stem Cell Research. Among the application segments, in 2022, the bioproduction segment is estimated to account for the largest share of the cell culture market. The major factors contributing to the large market share of this segment are the consumption of cell culture products for commercial bioproduction and research. The rising demand for pharma and biopharma products, and the availability of funds used for research activities.
End user segment of cell culture market is further divided into Pharmaceutical & Biotechnology Companies and Academic & Research Institutes. The pharmaceutical & biotechnology companies segment was accounted for the largest share of the cell culture market. Factors driving the large market share of this segment are the high consumption of cell culture products in commercial & research bioproduction and relatively greater purchasing power than other end users.
By Product Type
· Consumables
o Media
§ Form
· Dry Form
· Liquid Form
§ Type
· Off-the-Shelf Media
· Custom Media
§ Source
· Serum-free Media
· Chemically Defined Media
· Classical Media
· Xeno-free/Animal Component Free
o Reagents
§ Growth Factors and Cytokines
§ Cryoprotective Reagents
§ Antibiotics/Antimycotics
§ Cell Dissociation Reagents
§ Buffers
§ Balanced Salt Solutions
§ Attachment and Matrix Factors
o Cells and Cell Lines
o Sera
§ Fetal Bovine Serum
§ Other Sera Types
o Cell Culture Vessels
§ Cell Culture Dishes
§ Cell Culture Plates
· 6 to 24-well Plates
· 48-well Plates
· 96 to 384-well Plates
§ Cell Culture Flasks
§ Roller Bottles
· Equipment
o Bioreactors
o Biosafety Cabinets
o Incubators
o Cryopreservation Containers
o Refrigerators and Freezers
o Sterilizers
o Microscopes
o Centrifuges
o Cell Counters
o Water Baths
By Application
· Bioproduction
o Monoclonal Antibody Production
o Therapeutic Protein Production
o Vaccine Production
o Cell and Gene therapy
· Drug Screening & Development
· Cancer Research
· Stem Cell Research
By End User
· Pharmaceutical & Biotechnology Companies
· Academic & Research Institutes
1. Global Cell Culture Market Introduction and Market Overview
1.1. Objectives of the Study
1.2. Global Cell Culture Market Scope and Market Estimation
1.2.1.Global Cell Culture Overall Market Size, Revenue & Volume (US$ Mn & Million Units), Market CAGR (%), Market forecast (2023 - 2032)
1.2.2.Global Cell Culture Market Revenue Share (%) and Growth Rate (Y-o-Y) from 2019 - 2032
1.3. Market Segmentation
1.3.1.Product Type of Global Cell Culture Market
1.3.2.Application of Global Cell Culture Market
1.3.3.End User of Global Cell Culture Market
1.3.4.Region of Global Cell Culture Market
2. Executive Summary
3. Market Factor Analysis
3.1. Global Cell Culture Market Industry Trends under COVID-19 Outbreak
3.1.1.Global COVID-19 Status Overview
3.1.2.Influence of COVID-19 Outbreak on Global Cell Culture Market Industry Development
3.2. Market Dynamics, By Region
3.2.1.Drivers
3.2.2.Limitations
3.2.3.Opportunities
3.2.4.Impact Analysis of Drivers and Restraints
3.3. Ecosystem / Value Chain Analysis
3.3.1.Raw Materials / Component Suppliers
3.3.2.Manufacturers / Vendors
3.3.3.Distributors
3.3.4.Buyers / End-users
3.3.5.Forward Integration & Backward Integration of Key Stakeholders
3.4. Global Cell Culture Market - Pricing Trends Analysis & Average Selling Prices (ASPs)
3.5. Analysis of Software and Services used in Cell Culture
3.6. End-User / Customer Preferences & Consumer Surveys
3.7. Technology Roadmap & Key Innovations /Developments
3.8. Key Mandates & Regulatory Scenario Analysis
3.9. Patents Landscape
3.10. Import & Export, By Countries (USD Million)
3.11. Key Mergers & Acquisitions, Expansions, JVs, Funding / VCs, etc.
3.12. Porter’s Five Forces Analysis
3.12.1. Bargaining Power of Suppliers
3.12.2. Bargaining Power of Buyers
3.12.3. Threat of Substitutes
3.12.4. Threat of New Entrants
3.12.5. Competitive Rivalry
3.13. PEST Analysis
3.13.1. Political Factors
3.13.2. Economic Factors
3.13.3. Social Factors
3.13.4. Technological Factors
3.14. SWOT Analysis
3.15. Russia-Ukraine War Impacts Analysis
3.16. ANSOFF Matrix
3.16.1. Market Penetration Strategy
3.16.2. Product Development Strategy
3.16.3. Market Development Strategy
3.16.4. Diversification Strategy
3.17. Inflation Impacts Analysis
3.17.1. Supply Side Impacts
3.17.2. Demand Side Impacts
3.17.3. Outlook in 2023 & Beyond
3.18. Market Investment Feasibility Analysis
3.19. Opportunity Map Analysis
3.20. Market Investment Opportunity Analysis (Top Investment Pockets), By Segments & By Regions
4. Global Cell Culture Market Estimates & Historical Trend Analysis (2019 - 2022)
5. Global Cell Culture Market Estimates & Forecast Trend Analysis, by Product Type
5.1. Global Cell Culture Market Revenue & Volume (US$ Mn & Million Units) Estimates and Forecasts, by Product Type, 2019 to 2032
5.1.1.Consumables
5.1.1.1. Media
5.1.1.1.1. Form
5.1.1.1.1.1. Dry Form
5.1.1.1.1.2. Liquid Form
5.1.1.1.2. Type
5.1.1.1.2.1. Off-the-Shelf Media
5.1.1.1.2.2. Custom Media
5.1.1.1.3. Source
5.1.1.1.3.1. Serum-free Media
5.1.1.1.3.2. Chemically Defined Media
5.1.1.1.3.3. Classical Media
5.1.1.1.3.4. Xeno-free/Animal Component Free
5.1.1.2. Reagents
5.1.1.2.1. Growth Factors and Cytokines
5.1.1.2.2. Cryoprotective Reagents
5.1.1.2.3. Antibiotics/Antimycotics
5.1.1.2.4. Cell Dissociation Reagents
5.1.1.2.5. Buffers
5.1.1.2.6. Balanced Salt Solutions
5.1.1.2.7. Attachment and Matrix Factors
5.1.1.3. Cells and Cell Lines
5.1.1.4. Sera
5.1.1.4.1. Fetal Bovine Serum
5.1.1.4.2. Other Sera Types
5.1.1.5. Cell Culture Vessels
5.1.1.5.1. Cell Culture Dishes
5.1.1.5.2. Cell Culture Plates
5.1.1.5.2.1. 6 to 24-well Plates
5.1.1.5.2.2. 48-well Plates
5.1.1.5.2.3. 96 to 384-well Plates
5.1.1.5.2.4. Cell Culture Flasks
5.1.1.5.2.5. Roller Bottles
5.1.1.6. Equipment
5.1.1.6.1. Bioreactors
5.1.1.6.2. Biosafety Cabinets
5.1.1.6.3. Incubators
5.1.1.6.4. Cryopreservation Containers
5.1.1.6.5. Refrigerators and Freezers
5.1.1.6.6. Sterilizers
5.1.1.6.7. Microscopes
5.1.1.6.8. Centrifuges
5.1.1.6.9. Cell Counters
5.1.1.6.10. Water Baths
6. Global Cell Culture Market Estimates & Forecast Trend Analysis, by Application
6.1. Global Cell Culture Market Revenue & Volume (US$ Mn & Million Units) Estimates and Forecasts, by Application, 2019 to 2032
6.1.1.Bioproduction
6.1.1.1. Monoclonal Antibody Production
6.1.1.2. Therapeutic Protein Production
6.1.1.3. Vaccine Production
6.1.1.4. Cell and Gene therapy
6.1.2.Drug Screening & Development
6.1.3.Cancer Research
6.1.4.Stem Cell Research
7. Global Cell Culture Market Estimates & Forecast Trend Analysis, by End User
7.1. Global Cell Culture Market Revenue & Volume (US$ Mn & Million Units) Estimates and Forecasts, by End User, 2019 to 2032
7.1.1.Pharmaceutical & Biotechnology Companies
7.1.2.Academic & Research Institutes
8. Global Cell Culture Market Estimates & Forecast Trend Analysis, by Region
8.1. Global Cell Culture Market Revenue & Volume (US$ Mn & Million Units) Estimates and Forecasts, by Region, 2019 to 2032
8.1.1.North America
8.1.2.Europe
8.1.3.Asia Pacific
8.1.4.Middle East & Africa
8.1.5.South America
9. North America Cell Culture Market: Estimates & Forecast Trend Analysis
9.1. North America Cell Culture Market Assessments & Key Findings
9.1.1.Cell Culture Market Introduction
9.1.2.Cell Culture Market Size & Volume Estimates and Forecast (US$ Million & Million Units) (2019 – 2031)
9.1.2.1. By Product Type
9.1.2.2. By Application
9.1.2.3. By End User
9.1.2.4. By Country
9.1.2.4.1. The U.S.
9.1.2.4.2. Canada
9.1.2.4.3. Mexico
10. Europe Cell Culture Market: Estimates & Forecast Trend Analysis
10.1. Europe Cell Culture Market Assessments & Key Findings
10.1.1. Cell Culture Market Introduction
10.1.2. Cell Culture Market Size & Volume Estimates and Forecast (US$ Million & Million Units) (2019 – 2031)
10.1.2.1. By Product Type
10.1.2.2. By Application
10.1.2.3. By End User
10.1.2.4. By Country
10.1.2.4.1. Germany
10.1.2.4.2. U.K.
10.1.2.4.3. France
10.1.2.4.4. Italy
10.1.2.4.5. Spain
10.1.2.4.6. Russia
10.1.2.4.7. Rest of Europe
11. Asia Pacific Cell Culture Market: Estimates & Forecast Trend Analysis
11.1. Asia Pacific Market Assessments & Key Findings
11.1.1. Cell Culture Market Introduction
11.1.2. Cell Culture Market Size & Volume Estimates and Forecast (US$ Million & Million Units) (2019 – 2031)
11.1.2.1. By Product Type
11.1.2.2. By Application
11.1.2.3. By End User
11.1.2.4. By Country
11.1.2.4.1. China
11.1.2.4.2. Japan
11.1.2.4.3. India
11.1.2.4.4. Australia
11.1.2.4.5. South Korea
11.1.2.4.6. ASEAN
11.1.2.4.7. Rest of Asia Pacific
12. Middle East & Africa Cell Culture Market: Estimates & Forecast Trend Analysis
12.1. Middle East & Africa Market Assessments & Key Findings
12.1.1. Cell Culture Market Introduction
12.1.2. Cell Culture Market Size & Volume Estimates and Forecast (US$ Million & Million Units) (2019 – 2031)
12.1.2.1. By Product Type
12.1.2.2. By Application
12.1.2.3. By End User
12.1.2.4. By Country
12.1.2.4.1. U.A.E.
12.1.2.4.2. Saudi Arabia
12.1.2.4.3. Egypt
12.1.2.4.4. South Africa
12.1.2.4.5. Rest of Middle East & Africa
13. South America Cell Culture Market: Estimates & Forecast Trend Analysis
13.1. South America Market Assessments & Key Findings
13.1.1. Cell Culture Market Introduction
13.1.2. Cell Culture Market Size & Volume Estimates and Forecast (US$ Million & Million Units) (2019 – 2031)
13.1.2.1. By Product Type
13.1.2.2. By Application
13.1.2.3. By End User
13.1.2.4. By Country
13.1.2.4.1. Brazil
13.1.2.4.2. Argentina
13.1.2.4.3. Colombia
13.1.2.4.4. Rest of South America
14. Competition Landscape
14.1. Cell Culture Market Competition Index, By Leading Players
14.2. Cell Culture Market Competition Matrix & Benchmarking, by Leading Players / Innovators / Emerging Players / New Entrants
14.3. Cell Culture Market Competition White Space Analysis, By Application/ End-user
14.4. Cell Culture Market Competition Heat Map Analysis, By Product / Services / Solutions
14.5. Cell Culture Market Competition Regional Intensity Map Analysis, By Geographies Served
14.6. Cell Culture Market Concentration & Company Market Shares (%) Analysis, 2022
14.7. Cell Culture Market Competition Quadrant Analysis, By Leading Players / Innovators / Emerging Players / New Entrants
15. Company Profiles
16. Agilent Technologies
16.1.1. Company Overview & Key Stats
16.1.2. Financial Performance & KPIs
16.1.3. Product / Service / Solutions Portfolio & Applications / End-uses
16.1.4. Business Strategy & Recent Developments
* Similar details would be provided for all the players mentioned below
16.2. Avantor, Inc.
16.3. Becton, Dickinson and Company
16.4. Bio-Rad Laboratories, Inc.
16.5. BioSpherix, Ltd.
16.6. Bio-Techne Corporation
16.7. Corning Incorporated
16.8. Cytiva, Eppendorf SE
16.9. FUJIFILM Holdings Corporation
16.10. Getinge AB
16.11. Greiner Bio-One GmbH
16.12. HiMedia Laboratories
16.13. Lonza Group Ltd.
16.14. Merck KGaA
16.15. Miltenyi Biotec B.V. & Co. KG
16.16. PromoCell GmbH
16.17. Sartorius AG
16.18. Thermo Fisher Scientific, Inc.
16.19. VWR International, LLC
16.20. Others**
17. Research Methodology
17.1. External Sources / Databases
17.2. Internal Proprietary Database
17.3. Primary Research
17.4. Secondary Research
17.5. Assumptions
17.6. Limitations
17.7. Report FAQs
18. Research Findings & Conclusion
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